YBX1 anticorps

N° du produit ABIN6938790

L’anticorps Souris Monoclonal anti-YBX1 a été validé pour IHC (f). Il convient pour détecter YBX1 dans des échantillons de Humain.

Aperçu rapide pour YBX1 anticorps (ABIN6938790)

Antigène: YBX1 (Y Box Binding Protein 1 (YBX1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp YBX1 est non-conjugé

Application: Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Clone: YBX1-2430

Détail du produit anti-YBX1 anticorps

Specificité: The specificity of this monoclonal antibody to its intended target was validated by HuProtTM Array, containing more than 19,000, full-length human proteins. Y-box binding protein-1 (YBX1) is the prototypic member of the cold shock protein family that fulfills numerous cellular functions. In the nucleus, YBX1 protein orchestrates transcription of proliferation-related genes, whereas in the cytoplasm it associates with mRNA and directs translation. In human tumor entities, such as breast, lung and prostate cancer, cellular YBX1 expression indicates poor clinical outcome, suggesting that YBX1 is an attractive marker to predict patients' prognosis.

Réactivité croisée (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Recombinant human full-length YBX1 protein

Isotype: IgG2b kappa

Information d'application

Indications d'application:

Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

Positive_Control: MCF-7, HEK293 or PC12 cells. Prostate, Breast or Lung Carcinoma.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur YBX1

Antigène: YBX1 (Y Box Binding Protein 1 (YBX1))

Autre désignation: YBX1

Sujet: BP-8, CSDA2, CSDB, DBPB, MDR-NF1, NSEP-1, NSEP1, YB-1, YB1,YBX1 / Y-box Binding Protein 1 / YB-1 (Tumor Biomarker)
Cellular localisation: Cytoplasmic and Nuclear

Poids moléculaire: 36kDa

ID gène: 4904, 473583

UniProt: P67809

Pathways: Regulation of Muscle Cell Differentiation